 |
|
What is Cancer? |

|
Cancer is a chronic disease characterized by uncontrolled
cell division and abnormal cell growth in body. Cells become increasingly
abnormal and occupy a greater portion of the tissue, lead to an invasion
of connective tissue into blood or lymphatic system and spread to
secondary sites (metastasis). Usually genes mutation lead to alternate
cells structure and affect normal tissue functions. Altered cells
must be amplified to generate billions of cell that contribute a cancer.
As it takes time to generate these errors and cell numbers, it follows
that the longer one lives, the more likely one is to get cancer. Cancer
seriously lead to death, but are not always lethal. About 20-50 %
Canadian deaths are contributed to cancer. |
 |
Cause Factors |
 |
There are multiple cause but lifestyle factor has
a major influence. Breast and prostate cancer are very common in western
countries. Cervical and stomach cancer are more prevalent in Asia.
In North America, lung cancer is most common in men and breast cancer
is most common in women. Major factors that cause cancer are smoking,
diet, sex hormones and family history. Smoking is main cause of lung
and mouth cancers and accounts for half of bladder and kidney growths.
Carcinogens in the cigarettes when inhaled and is taken into bloodstream,
can cause defection in genes. Food contain high fat and salt content,
and alcohol, increase common risk. Vegetables, fruits, dietary fibers
and Vitamin C decrease cancer risk. |
 |
Signs and Symptoms |
 |
Signs and symptoms is varied from cancer to cancer.
As cancer diagnosed earlier has higher chance to cure, regular check-up
and perform screening examination are highly recommended. If any changes
in body function, or appearance, should consult to the physicians
and other health professionals.
Possible signs and symptoms of cancer are coughing (lung cancer);
lumps (breast and prostate); a white patch on cervix, mouth-leukoplakia
(lung and esophagus cancer); bleeding, pain, fluid draining (stomach,
colon cancer). |
 |
Current Cancer Treatment |
 |
Treatment of cancer based on removal or killing of
tumor cell. Nowadays, oncologist use different treatments modulate
for all reasons. |
Primary treatment: |
- as a principle method of treatment such
as surgery or radiation.
|
Adjuvant treatment: |
- use in conjunction with primary method in
an attempt to get rid of any micrometastasis. For example:
chemotherapy.
|
Palliative treatment: |
- use only to improve life quality before
death. For example, stop or reduce amount of pain, not intended
to cure cancer.
|
|
 |
Three common classical treatment: |
 |
Surgery: |
- Usually use as primary treatment, result to remove all
tumor cells.
- Approximate 90% of cures of solid malignant tumors are
achieved.
- Shortcomings: not effective against metastasis, cannot
use on some vital organs that cannot be removed.
|
Radiation therapy: |
- Radiation such as X-ray and gamma rays damage
DNA single and double strand structure, cell die by apoptotic
pathway (programmed cell suicide). Usually cancer cells
are more radiosensitive than normal healthy cells.
- Used when tumors are localized as primary
or adjuvant treatment.
- Shortcomings: cannot treat metastasis, side
effects
- Treatment target to avoid irradiation of
normal cells
- new modifications:
- 3-D images of tumors and function
- position-emission tomography(PET)
- magnetic resonance imaging (MRI)
|
Chemotherapy: |
- Use to treat metastasis (late cancer stages)
- Drug use are toxic to proliferating cells, prevent cells
multiply, interfere DNA replicability.
- Induce apoptosis of cells, disrupt cell cycles
- Different drug combinations for different cancer
- Shortcomings: damage normal cells, hair loss, nausea and
vomiting, tumor cells become resistant to drugs.
|
|
 |
Best form of treatment is prevention and early detection.
The smaller the number and less malignant the nature of cancer cells,
greater probability of cure. There are screening programs for early
detection of cervical, breast and colon cancer. |
|